Scattered around FusionFall are three types of missions: world missions, which are basic tasks; guide missions, which ask you to complete an important goal on behalf of the Cartoon Network character guiding you through the current area; and nano missions, which reward you with a miniature version of a Cartoon Network character, known as a nano. Complete world and guide missions to obtain special items and Fusion matter, which you must collect in a specific quantity before a new nano mission becomes available.
You’ll eventually collect 36 nanos, each of whom confers bonuses of your choosing, such as the ability to run faster or jump higher. Up to three nanos can accompany you at any given time; each one is a different type — Blaston, Adaptium, or Cosmix — that gives you an advantage against certain types of Fusion monsters, so call on the right ones for the current confrontation. Use your Nanos wisely: they begin to tire as soon as you activate them and quickly wear down while fighting Fusion monsters and Fusions. They’ll need to rest before you can call on them again.