The only issue I have with it thus far, is the 'checkpoint' saves and the 'find rare collectibles'.
Checkpoints pop a save at certain times, and if you fail to proceed/die whatever, you go back to that point. Ok... but, whats very annoying is when that point is back before you have to go gather this, click that, do some other thing, and pick up some much needed tool or crafting items all in that area with zero threat. Meaning, everytime you die, you have to redo all those mundane tasks again before proceeding to the area you die in. Gets annoying.
The 'collectibles' thing is just needless. I mean, you are running for your life, or trudging through a field of rotting corpses and think: Hmm... I will go look under every body for something that might be worth holding onto... or whats in this corner as a horde of flesh eating monsters are right on my tail ... nope? nothing in there? ok, I will know not to bother with that corner after the checkpoint reloads cause I just died trying to look there.
Other than those two things, the game is top notch so far.
I beat this a few months ago... first half is great, then the story goes off the rails pretty abruptly. Still, I enjoyed it. Loved the main character, which had really great voice acting. Intrigued about the sequel. If they can write a better villain (or better yet, just make the plague setting the "villain") it could be amazing.
I didn't mind the checkpoints or the collectibles. Checkpoints seemed fair to me for the most part, and I have low tolerance for them in general. I don't think I died a whole lot in the first half, though. You have to scrounge around for supplies, so in that context, finding collectibles didn't seem out of place.